Description

(1-Fluorocyclopropyl)Methanol is a versatile fluorinated building block of significant interest in advanced organic synthesis. Its unique structure, featuring a strained cyclopropane ring and a fluoromethyl alcohol moiety, makes it a valuable intermediate for introducing conformational rigidity and fluorine atoms into target molecules. This compound is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for constructing fluorinated bioactive molecules, including potential enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the fluorine atom can enhance metabolic stability and bioavailability.
• Material Science Precursor: Serves as a monomer or functionalization agent for creating specialty polymers with tailored surface properties.
• Ligand and Catalyst Development: Employed in the synthesis of chiral ligands or organocatalysts that incorporate the cyclopropyl group for steric control.
• Fluorine Chemistry Research: A fundamental reagent for studying the reactivity and properties of fluorinated small-ring systems in academic and industrial R&D settings.
• Prosthetic Group Synthesis: Useful for preparing fluorinated tags and probes used in medicinal chemistry and diagnostic imaging.

Basic Information

Product Name	(1-Fluorocyclopropyl)Methanol
CAS No.	154985-93-0
Molecular Formula	C4H7FO
Molecular Weight	90.10 g/mol
Synonyms	1-Fluorocyclopropanemethanol; (1-Fluorocyclopropyl)carbinol; 1-Fluorocyclopropylmethanol; α-(Fluorocyclopropyl)methanol; Fluorocyclopropylmethanol; Cyclopropanemethanol, 1-fluoro-; (Fluorocyclopropyl)methanol
EINECS	Contact for details

Quality Control

Our (1-Fluorocyclopropyl)Methanol is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, identity, and impurity profiles. We support development and commercial projects with material that meets rigorous internal specifications and can provide guidance on relevant analytical standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, maintaining the material at 2-8°C under an inert atmosphere is recommended to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.