Description

6-(Dimethylamino)Nicotinonitrile is a versatile heterocyclic building block featuring a nitrile group and a dimethylamino substituent on a pyridine ring. This molecular structure makes it a valuable intermediate for synthesizing more complex pharmacologically active compounds and functional materials. It is primarily sought after by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its pyridine-based scaffold.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials and dyes due to its electron-donating dimethylamino group.
• Chemical Biology Probes: Utilized as a building block for synthesizing fluorescent tags or molecular probes for biological research.
• Custom Synthesis and Contract Manufacturing: A critical raw material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	6-(Dimethylamino)Nicotinonitrile
CAS No.	154924-17-1
Molecular Formula	C8H9N3
Molecular Weight	147.18 g/mol
Synonyms	6-(Dimethylamino)pyridine-3-carbonitrile; 3-Cyano-6-(dimethylamino)pyridine; 6-Dimethylaminonicotinonitrile; 2-(Dimethylamino)-5-cyanopyridine; 5-Cyano-2-(dimethylamino)pyridine; Nicotinonitrile, 6-(dimethylamino)-; 154924-17-1; 6-(N,N-Dimethylamino)nicotinonitrile
EINECS	Contact for details

Quality Control

Our 6-(Dimethylamino)Nicotinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.