Description

E-2-(3,3-Dimethylbutenyl)Boronic Acid Pinacol Ester is a high-value organoboron building block, specifically a protected boronic ester, essential for modern synthetic chemistry. Its primary value lies in enabling precise Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds under mild conditions. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for constructing complex molecular scaffolds in drug discovery and development programs.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides with tailored properties.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable, air-handleable organoboron coupling partner with aryl/vinyl halides or triflates.
• Material Science & OLED Development: Building block for creating organic semiconductors, light-emitting materials, and advanced polymers.
• Academic & Contract Research: Fundamental reagent for methodological development and complex natural product synthesis in research laboratories.
• Ligand & Catalyst Preparation: Used in the synthesis of specialized ligands for transition metal catalysis.

Basic Information

Product Name	E-2-(3,3-Dimethylbutenyl)Boronic Acid Pinacol Ester
CAS No.	154820-99-2
Molecular Formula	C12H23BO2
Molecular Weight	210.12 g/mol
Synonyms	2-(3,3-Dimethylbut-1-en-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (E)-2-(3,3-Dimethylbut-1-enyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (E)-3,3-Dimethyl-1-butenylboronic Acid Pinacol Ester; Pinacol (E)-2-(3,3-Dimethylbut-1-en-1-yl)boronate; E-3,3-Dimethyl-1-butenylboronic Acid Pinacol Ester; Boronic acid, B-[(1E)-3,3-dimethyl-1-buten-1-yl]-, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane ester
EINECS	Contact for details

Quality Control

Our E-2-(3,3-Dimethylbutenyl)Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes comprehensive analytical characterization, including NMR, HPLC, and GC analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformance to specifications. Our quality system is designed to support cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) in a cool, dry place at 2-8°C to minimize decomposition. This compound is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air or moisture should be avoided. The original container should be allowed to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥95% (Typical 97-99%)
Isomeric Purity (E/Z Ratio)	≥95:5 (E:Z)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.