Description

1-Pentanone, 2-Fluoro-3-Methyl-1-Phenyl-, (R*,R*)- (9Ci) is a chiral, fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its unique structural features, combining a phenyl group with fluorine and methyl substituents on a pentanone backbone, which are valuable for modulating the physicochemical properties of target molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients, as well as by manufacturers of specialty chemicals and liquid crystals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly where fluorine substitution is used to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where its fluorinated structure can contribute to improved activity and environmental profile.
• Liquid Crystal Materials: Acts as a potential intermediate or dopant in the synthesis of fluorinated liquid crystals for display technologies.
• Organic Electronic Materials: Investigated as a building block for novel organic semiconductors and charge-transport materials.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in academic and industrial research focused on developing new chiral catalysts.
• Flavor & Fragrance Chemistry: May be used in the synthesis of complex aroma chemicals, leveraging its ketone functionality and aromatic character.

Basic Information

Product Name	1-Pentanone, 2-Fluoro-3-Methyl-1-Phenyl-, (R*,R*)- (9Ci)
CAS No.	154669-93-9
Molecular Formula	C12H15FO
Molecular Weight	194.25 g/mol
Synonyms	(2R*,3R*)-2-Fluoro-3-methyl-1-phenylpentan-1-one; 2-Fluoro-3-methyl-1-phenyl-1-pentanone, (R*,R*)-; 1-Phenyl-2-fluoro-3-methyl-1-pentanone; (R*,R*)-rel-2-Fluoro-3-methyl-1-phenylpentan-1-one; (rel-(R*,R*))-2-Fluoro-3-methyl-1-phenyl-1-pentanone; 154669-93-9; 2-Fluoro-3-methyl-1-phenylpentan-1-one
EINECS	Contact for details

Quality Control

Our production of 1-Pentanone, 2-Fluoro-3-Methyl-1-Phenyl-, (R*,R*)- (9Ci) adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and industrial use. Each lot undergoes comprehensive analysis, including chiral purity assessment, to meet the exacting requirements of advanced synthetic applications. A detailed Certificate of Analysis (COA) providing specifications for identity, purity, and chiral excess is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (diastereomeric excess)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.