Description

(2S,4S)-(-)-2,4-Bis(Diphenylphosphino)Pentane(Norbornadiene)Rhodium(I)Hexafluorophosphate is a high-purity, chiral organometallic complex widely used as a homogeneous catalyst precursor. Its value lies in its well-defined stereochemistry and air-sensitive nature, which are critical for achieving high selectivity and activity in asymmetric synthesis. This product is essential for researchers and process chemists in the pharmaceutical, fine chemical, and advanced materials sectors who require precise control over stereochemical outcomes.

Application

• Asymmetric Hydrogenation: A key catalyst precursor for the enantioselective reduction of prochiral olefins, ketones, and imines, crucial for producing chiral pharmaceutical intermediates.
• Pharmaceutical Synthesis: Enables the production of single-enantiomer active pharmaceutical ingredients (APIs) for drugs targeting central nervous system disorders, cardiovascular diseases, and anti-infectives.
• Fine Chemical Manufacturing: Used in the synthesis of complex, high-value fragrance and flavor compounds, agrochemicals, and specialty polymers where chirality dictates function.
• Academic & Industrial R&D: Serves as a benchmark catalyst in method development and mechanistic studies for exploring new asymmetric transformations.
• Catalyst Ligand Evaluation: The (S,S)-BDPP ligand framework can be studied in situ for its coordination chemistry and efficacy with various metal centers beyond rhodium.

Basic Information

Product Name	(2S,4S)-(-)-2,4-Bis(Diphenylphosphino)Pentane(Norbornadiene)Rhodium(I)Hexafluorophosphate
CAS No.	154661-57-1
Molecular Formula	C41H40F6P3Rh
Molecular Weight	846.58 g/mol
Synonyms	(S,S)-BDPP-Rh(NBD)PF6; (2S,4S)-(-)-2,4-Bis(diphenylphosphino)pentane(norbornadiene)rhodium(I) tetrafluoroborate (common mis-assignment); Rhodium(I)-(S,S)-BDPP norbornadiene hexafluorophosphate; (S,S)-2,4-Bis(diphenylphosphino)pentane rhodium(I) norbornadiene complex; [Rh((S,S)-BDPP)(nbd)]PF6; (S,S)-Chiraphos derivative rhodium complex; Asymmetric hydrogenation catalyst precursor Rh-BDPP
EINECS	Contact for details

Quality Control

Every batch of our (2S,4S)-(-)-2,4-Bis(Diphenylphosphino)Pentane(Norbornadiene)Rhodium(I)Hexafluorophosphate is synthesized and handled under strict inert atmosphere conditions to preserve its catalytic activity. We employ advanced analytical techniques, including NMR and HPLC, to verify high chiral purity and chemical identity. Certificates of Analysis (COA) detailing specific batch data are provided to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a freezer. This compound is easily oxidized and moisture-sensitive; prolonged exposure to air or ambient conditions will lead to decomposition and loss of catalytic activity. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Chiral Purity (Chiral HPLC)	≥ 99% ee
Solubility	Soluble in dichloromethane, acetone; sparingly soluble in alcohols

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.