Description

(4R,5R)-2-Butyl-4-N,4-N,5-N,5-n-Tetramethyl-1,3,2-Dioxaborolane-4,5-Dicarboxamide CAS NO 154420-26-5 is a high-purity, chiral dioxaborolane derivative, a critical class of compounds valued for their utility as intermediates and reagents in advanced synthetic chemistry. Its primary commercial value lies in its role as a key chiral building block and boron-containing synthon for the stereoselective construction of complex molecules. This product is essential for research and development laboratories and production facilities in the pharmaceutical and agrochemical sectors, where precise stereochemistry is paramount for developing active ingredients.

Application

• Pharmaceutical Intermediate: A crucial chiral precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological and metabolic diseases.
• Asymmetric Synthesis Reagent: Used in stereoselective carbon-boron bond formation reactions, such as Suzuki-Miyaura cross-couplings, to create complex, enantiomerically pure compounds.
• Agrochemical Research: Serves as a building block for developing new chiral herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science Precursor: Employed in the research of boron-doped organic electronic materials and polymers with specific optical or conductive properties.
• Catalyst Ligand Development: The structural framework can be utilized to develop novel chiral ligands for transition metal catalysis.
• Academic & R&D: A valuable tool for methodological development in organic synthesis and medicinal chemistry within university and corporate research labs.

Basic Information

Item	Information
Product Name	(4R,5R)-2-Butyl-4-N,4-N,5-N,5-n-Tetramethyl-1,3,2-Dioxaborolane-4,5-Dicarboxamide
CAS No.	154420-26-5
Molecular Formula	C14H27BN2O4
Molecular Weight	298.19 g/mol
Synonyms	(4R,5R)-2-Butyl-4,5-bis(dimethylcarbamoyl)-1,3,2-dioxaborolane; (4R,5R)-2-Butyl-4,5-bis(N,N-dimethylcarboxamido)-1,3,2-dioxaborolane; (4R,5R)-4,5-Bis(dimethylcarbamoyl)-2-butyl-1,3,2-dioxaborolane; Chiral Dioxaborolane Dicarboxamide; (4R,5R)-Dioxaborolane Derivative; Butyl Tetramethyl Dioxaborolane Dicarboxamide; Boro-ester Amide Derivative
EINECS	Contact for details

Quality Control

Our (4R,5R)-2-Butyl-4-N,4-N,5-N,5-n-Tetramethyl-1,3,2-Dioxaborolane-4,5-Dicarboxamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants or storing under an inert atmosphere such as nitrogen or argon to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.