Description

2(3H)-Furanone,5-Ethoxydihydro-4-Methyl-4-(Trifluoromethyl)-,trans-(9Ci) CAS NO 154389-74-9 is a specialized fluorinated furanone derivative, a high-value intermediate prized for its unique structural motif. This compound matters for its role as a critical building block in advanced organic synthesis, particularly for introducing the trifluoromethyl group, which is essential for modulating the physicochemical properties of target molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the trifluoromethyl group contributes to improved efficacy and environmental profile.
• Material Science Research: Employed in the development of novel fluorinated polymers and liquid crystals with specific optical and electronic properties.
• Organic Synthesis Building Block: A versatile reagent for constructing complex heterocyclic frameworks in academic and industrial research settings.
• Flavor & Fragrance Chemistry: Potential use in the synthesis of novel aroma chemicals, leveraging the furanone core structure.

Basic Information

Product Name	2(3H)-Furanone,5-Ethoxydihydro-4-Methyl-4-(Trifluoromethyl)-,trans-(9Ci)
CAS No.	154389-74-9
Molecular Formula	C8H11F3O3
Molecular Weight	212.17 g/mol
Synonyms	trans-5-Ethoxy-4-methyl-4-(trifluoromethyl)dihydrofuran-2(3H)-one; 4-Methyl-4-(trifluoromethyl)-5-ethoxydihydro-2(3H)-furanone, trans-; 5-Ethoxy-4-methyl-4-(trifluoromethyl)tetrahydro-2-furanone; Dihydro-5-ethoxy-4-methyl-4-(trifluoromethyl)-2(3H)-furanone, (trans)-; (4R*,5R*)-5-Ethoxy-4-methyl-4-(trifluoromethyl)dihydrofuran-2(3H)-one; (rel)-(4R,5R)-5-Ethoxy-4-methyl-4-(trifluoromethyl)dihydrofuran-2(3H)-one
EINECS	Contact for details

Quality Control

Our 2(3H)-Furanone,5-Ethoxydihydro-4-Methyl-4-(Trifluoromethyl)-,trans-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistent isomeric composition. Standard quality parameters include assay by GC/HPLC, confirmation of stereochemistry, and control of related substances. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Isomeric Purity (trans-)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.