Description

1-(3-Chloro-2,4-Difluorophenyl)Ethanone is a high-purity fluorinated aromatic ketone building block of significant importance in advanced organic synthesis. Its precise molecular architecture, featuring chloro and difluoro substituents, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders and anti-infectives.
• Agrochemical Synthesis: Serves as a crucial building block for manufacturing advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance bioavailability and environmental stability.
• Material Science Research: Used in the synthesis of specialty polymers and liquid crystals, where the difluorophenyl moiety influences material properties like thermal stability and dielectric constant.
• Organic Electronics: Employed as a precursor for electron-transport materials and small-molecule semiconductors in OLED and OFET applications.
• Chemical Research & Development: A versatile reagent for exploring new coupling reactions and synthesizing complex fluorinated aromatic systems in academic and industrial labs.

Basic Information

Product Name	1-(3-Chloro-2,4-Difluorophenyl)Ethanone
CAS No.	154258-06-7
Molecular Formula	C8H5ClF2O
Molecular Weight	190.57 g/mol
Synonyms	3'-Chloro-2',4'-Difluoroacetophenone; 1-(3-Chloro-2,4-difluorophenyl)ethan-1-one; 3-Chloro-2,4-difluoroacetophenone; 2,4-Difluoro-3-chloroacetophenone; 154258-06-7; Ethanone, 1-(3-chloro-2,4-difluorophenyl)-; Acetophenone, 3'-chloro-2',4'-difluoro-
EINECS	Contact for details

Quality Control

Our 1-(3-Chloro-2,4-Difluorophenyl)Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.