Description

3-Bromo-5-Chlorophenylethanone is a high-purity halogenated aromatic ketone building block of significant importance in advanced organic synthesis. Its precise molecular architecture makes it a critical intermediate for constructing complex molecules with specific electronic and steric properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a precursor for organic electronic materials, including ligands for metal-organic frameworks (MOFs) and components for organic light-emitting diodes (OLEDs).
• Chemical Research & Development: A versatile reagent for cross-coupling reactions, such as Suzuki and Buchwald-Hartwig couplings, to create complex biaryl structures.
• Ligand and Catalyst Preparation: Used to synthesize specialized ligands for asymmetric catalysis and transition metal complexes.
• Fine Chemical Production: Intermediate in the multi-step synthesis of dyes, pigments, and other performance chemicals.

Basic Information

Product Name	3-Bromo-5-Chlorophenylethanone
CAS No.	154257-85-9
Molecular Formula	C8H6BrClO
Molecular Weight	233.49 g/mol
Synonyms	1-(3-Bromo-5-chlorophenyl)ethanone; 3'-Bromo-5'-chloroacetophenone; 3-Bromo-5-chloroacetophenone; 1-Acetyl-3-bromo-5-chlorobenzene; Ethanone, 1-(3-bromo-5-chlorophenyl)-; 3-Bromo-5-chlorophenyl methyl ketone; 154257-85-9; 3-Br-5-Cl-C6H3COCH3
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Chlorophenylethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent lot-to-lot quality. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our production adheres to cGMP principles where applicable, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.