Description

n-(Chloroacetyl)-Alanine Methyl Ester CAS NO 153842-00-3 is a versatile and high-purity chemical building block used in advanced organic synthesis. This compound is valued for its reactive chloroacetyl group and protected amino acid functionality, enabling precise molecular construction. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for applications such as peptide mimetics and active ingredient development.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel peptide-based drugs and protease inhibitors.
• Agrochemical Synthesis: Used in the development of advanced herbicides and plant growth regulators.
• Bioconjugation Chemistry: Serves as a reagent for modifying peptides, proteins, and other biomolecules.
• Custom Organic Synthesis: Employed in contract research and manufacturing (CRO/CMO) for constructing complex molecular architectures.
• Academic & Industrial Research: A valuable tool in medicinal chemistry for structure-activity relationship (SAR) studies.
• Chemical Biology Probes: Used to create activity-based probes for studying enzyme function.

Basic Information

Product Name	n-(Chloroacetyl)-Alanine Methyl Ester
CAS No.	153842-00-3
Molecular Formula	C6H10ClNO3
Molecular Weight	179.60 g/mol
Synonyms	Methyl 2-(2-Chloroacetamido)propanoate; N-Chloroacetyl-L-alanine methyl ester; L-Alanine, N-(chloroacetyl)-, methyl ester; (2S)-2-[(2-Chloroacetyl)amino]propanoic acid methyl ester; Alanine, N-chloroacetyl-, methyl ester; Chloroacetylaminoalanine methyl ester; Methyl N-chloroacetylanilinate
EINECS	Contact for details

Quality Control

Our n-(Chloroacetyl)-Alanine Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.