Description

n-Butyl (2R,3S)-(-)-2,3-Epoxybutyrate CAS NO 153830-19-4 is a high-value chiral epoxide ester, serving as a critical chiral building block and intermediate in asymmetric synthesis. Its defined stereochemistry is essential for imparting specific biological activity and optical purity in advanced pharmaceutical compounds. This product is primarily required by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of active pharmaceutical ingredients (APIs), fine chemicals, and liquid crystals.

Application

• Chiral Intermediate for Pharmaceutical APIs: A key synthon in the asymmetric synthesis of complex drug molecules, particularly in antiviral, anticancer, and cardiovascular therapies.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators for enhanced efficacy and environmental safety.
• Liquid Crystal Precursor: Acts as a chiral dopant or building block in the manufacture of advanced liquid crystal displays (LCDs) and optical materials.
• Fine Chemical and Flavor/Fragrance Intermediate: Employed in the synthesis of enantiomerically pure flavors, fragrances, and other high-value specialty chemicals.
• Academic and Industrial R&D: A valuable reagent for methodological development in organic chemistry, catalysis, and stereoselective transformation studies.
• Polymer Modification: Used to introduce chiral epoxy functionalities into polymer chains for specialized material properties.

Basic Information

Product Name	n-Butyl (2R,3S)-(-)-2,3-Epoxybutyrate
CAS No.	153830-19-4
Molecular Formula	C8H14O3
Molecular Weight	158.20 g/mol
Synonyms	(-)-2,3-Epoxybutyric Acid Butyl Ester; (2R,3S)-2,3-Epoxybutanoic Acid Butyl Ester; Butyl (2R,3S)-2,3-Epoxybutanoate; (2R,3S)-(-)-Butyl Glycidate; n-Butyl (2R,3S)-2,3-Epoxybutyrate; (R,S)-trans-Butyl Glycidate; Butyl trans-2,3-Epoxybutyrate; Chiral Butyl Glycidate
EINECS	Contact for details

Quality Control

Our n-Butyl (2R,3S)-(-)-2,3-Epoxybutyrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical purity determination by HPLC/GC, to ensure it meets the stringent requirements for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing identity, purity, and specific impurities are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation by atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Specific Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.