Description

3,3-Diethoxy-1-Propenylboronic Acid Pinacol Ester is a high-value, protected boronic ester building block used in advanced organic synthesis. Its primary value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of modern pharmaceutical and agrochemical development. This compound is essential for research chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries who require reliable, high-purity intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates through palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific vinyl-boronate functionalities.
• Material Science Research: Employed in the development of organic electronic materials, such as polymers and small molecules for OLEDs and OFETs, where the vinyl group allows for further functionalization.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and other transition metal-catalyzed processes.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and bioconjugates for studying biological processes, leveraging the reactivity of the boronate ester group.
• Custom Synthesis and Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	3,3-Diethoxy-1-Propenylboronic Acid Pinacol Ester
CAS No.	153737-25-8
Molecular Formula	C₁₃H₂₅BO₄
Molecular Weight	256.15 g/mol
Synonyms	(1E)-3,3-Diethoxy-1-propen-1-ylboronic acid pinacol ester; (E)-3,3-Diethoxyprop-1-en-1-ylboronic acid pinacol ester; trans-3,3-Diethoxy-1-propenylboronic acid pinacol ester; 3,3-Diethoxy-1-propenylboronic acid, pinacol ester; (E)-3,3-Diethoxyallylboronic acid pinacol ester; Boronic acid, B-[(1E)-3,3-diethoxy-1-propen-1-yl]-, 2,2-dimethyl-1,3-propanediyl ester; 153737-25-8
EINECS	Contact for details

Quality Control

Our 3,3-Diethoxy-1-Propenylboronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive coupling reactions. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of GMP environments for advanced intermediates and we comply with relevant global regulatory frameworks including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isomeric Purity (E/Z Ratio)	≥ 95:5 (E:Z)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.