Description

Threo-Pentonic Acid, 2,3-Anhydro-2-C-Cyano-4,5-Dideoxy-, Methyl Ester (9Ci) is a specialized chiral building block and synthetic intermediate of significant interest in advanced organic synthesis. Its unique anhydro-cyano structure makes it a valuable precursor for constructing complex molecules with precise stereochemistry. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for nucleoside analogs and other bioactive molecules.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where specific stereochemistry is crucial for activity.
• Organic Synthesis Building Block: Serves as a versatile starting material for the synthesis of complex natural products, sugars, and heterocyclic compounds in academic and industrial R&D.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes and labeled compounds for studying biological mechanisms.
• Process Chemistry: Investigated for use in scalable, asymmetric synthesis routes within fine chemical and custom manufacturing organizations.

Basic Information

Product Name	Threo-Pentonic Acid, 2,3-Anhydro-2-C-Cyano-4,5-Dideoxy-, Methyl Ester (9Ci)
CAS No.	153431-53-9
Molecular Formula	C8H9NO4
Molecular Weight	183.16 g/mol
Synonyms	Methyl 2,3-anhydro-2-cyano-4,5-dideoxy-threo-pentonate; 2,3-Anhydro-2-cyano-4,5-dideoxy-threo-pentonic acid methyl ester; Methyl 2,3-anhydro-2-C-cyano-4,5-dideoxy-threo-pentonate; 153431-53-9; threo-Pentonic acid, 2,3-anhydro-2-C-cyano-4,5-dideoxy-, methyl ester (9CI)
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols. Each batch is characterized and tested to ensure identity, purity, and consistency, with specifications typically covering appearance, assay, chiral purity, and related substances. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support cGMP and ISO standards for research and development materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.