Description

m-Peg4-Benzaldehyde is a heterobifunctional polyethylene glycol (PEG) derivative featuring a benzaldehyde group and a methoxy terminus. This compound is a critical building block in bioconjugation and pharmaceutical development, enabling the site-specific modification of biomolecules and the creation of advanced drug delivery systems. It is primarily utilized by researchers and manufacturers in the fields of biopharmaceuticals, proteomics, and advanced material science for applications such as PEGylation, linker synthesis, and hydrogel formation.

Application

• Bioconjugation and PEGylation: Acts as a key linker for attaching therapeutic proteins, peptides, or antibodies to PEG chains to enhance pharmacokinetic properties.
• Drug Delivery System (DDS) Development: Used in the synthesis of stimuli-responsive prodrugs and nanocarriers for targeted cancer therapy.
• Cross-linking Agent: The aldehyde group reacts with amine-containing compounds (e.g., proteins, chitosan) to form hydrogels or cross-linked networks for tissue engineering scaffolds.
• Surface Functionalization: Modifies the surface of nanoparticles, quantum dots, or biosensors to introduce aldehyde groups for subsequent biomolecule immobilization.
• Antibody-Drug Conjugate (ADC) Linker: Serves as a cleavable or non-cleavable linker component in the construction of next-generation ADCs.
• Diagnostic Reagent Synthesis: Employed in the preparation of fluorescent or enzyme-labeled probes for immunoassays and diagnostic kits.

Basic Information

Product Name	m-Peg4-Benzaldehyde
CAS No.	153364-63-7
Molecular Formula	C16H24O6
Molecular Weight	312.36 g/mol
Synonyms	4-(2-(2-(2-(2-Methoxyethoxy)ethoxy)ethoxy)ethoxy)benzaldehyde; Benzaldehyde, 4-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]-; mPEG4-CHO; Methoxy-PEG4-aldehyde; PEG4 benzaldehyde; 1-(4-Formylphenoxy)-3,6,9,12-tetraoxapentadecane; O-(4-Formylphenyl)-O'-methyl-nonaethylene glycol; Aldehyde-PEG4-OMe
EINECS	Contact for details

Quality Control

Our m-Peg4-Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your research and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label. This product is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.