Description

4-Fluoro-4'-(Phenylethynyl)Benzophenone is a specialized organic compound featuring a benzophenone core functionalized with fluorine and a phenylethynyl group. This unique molecular architecture makes it a valuable high-purity building block and advanced intermediate for synthetic chemistry. It is primarily utilized by research institutions and industrial R&D departments engaged in the development of pharmaceuticals, agrochemicals, and advanced materials, where precise molecular control is critical.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for target molecules requiring a fluorinated benzophenone moiety.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and plant growth regulators where the fluorine atom enhances biological activity and metabolic stability.
• Material Science: Acts as a monomer or cross-linking agent in the production of specialty polymers, liquid crystals, and organic electronic materials.
• Organic Synthesis: A versatile building block for Suzuki, Sonogashira, and other cross-coupling reactions to construct complex conjugated systems.
• Chemical Research: Employed in academic and industrial labs for method development, catalysis studies, and exploring structure-activity relationships (SAR).

Basic Information

Product Name	4-Fluoro-4'-(Phenylethynyl)Benzophenone
CAS No.	153354-46-2
Molecular Formula	C21H13FO
Molecular Weight	300.33 g/mol
Synonyms	4-Fluoro-4'-(phenylethynyl)benzophenone; (4-Fluorophenyl)[4-(2-phenylethynyl)phenyl]methanone; 4'-Ethynyl-4-fluorobenzophenone (phenyl derivative); Benzophenone, 4-fluoro-4'-(phenylethynyl)-; 153354-46-2; 4-Fluoro-4'-(phenylethinyl)benzophenone
EINECS	Contact for details

Quality Control

Our 4-Fluoro-4'-(Phenylethynyl)Benzophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.