Description

Cyclopropanecarboxaldehyde, 2-(4-Methylphenyl)-, cis- (9Ci) is a specialized chiral aldehyde building block featuring a cyclopropane ring and a para-methylphenyl substituent. This compound matters as a high-value intermediate for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its unique cis-configured cyclopropane structure imparts specific steric and electronic properties. It is needed by R&D chemists and process development scientists working on novel active ingredients, including potential drug candidates, crop protection agents, and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of potential active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) or anti-inflammatory targets.
• Agrochemical Synthesis: Building block for developing novel pesticides or herbicides, where the cyclopropane moiety can enhance biological activity and stability.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands for asymmetric catalysis or as a scaffold in organometallic chemistry.
• Fine Chemical Research: Serves as a starting material for the exploration of new chemical entities and complex organic transformations in academic and industrial R&D.
• Material Science Precursor: Potential monomer or modifier in the synthesis of specialty polymers with tailored properties.
• Flavor & Fragrance Intermediate: May be utilized in the synthesis of complex aroma chemicals due to its aldehyde functionality and specific stereochemistry.

Basic Information

Item	Details
Product Name	Cyclopropanecarboxaldehyde, 2-(4-Methylphenyl)-, cis- (9Ci)
CAS No.	153198-69-7
Molecular Formula	C11H12O
Molecular Weight	160.21 g/mol
Synonyms	cis-2-(p-Tolyl)cyclopropanecarboxaldehyde; (1S,2R)-2-(4-Methylphenyl)cyclopropane-1-carbaldehyde; 2-(4-Methylphenyl)cyclopropanecarboxaldehyde, cis-; 2-(p-Tolyl)cyclopropanecarbaldehyde, cis-; cis-2-(4-Methylphenyl)-1-cyclopropanecarboxaldehyde; (1R,2S)-rel-2-(4-Methylphenyl)cyclopropanecarboxaldehyde; Cyclopropanecarboxaldehyde, 2-(4-methylphenyl)-, (1R,2S)-rel-; 2-(4-Methylphenyl)cyclopropanecarbaldehyde
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxaldehyde, 2-(4-Methylphenyl)-, cis- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, identity confirmation by IR and NMR spectroscopy, and determination of chemical purity. Certificates of Analysis (COA) with detailed specifications are provided to ensure traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. This material is easily oxidized (store under inert atmosphere).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (cis-isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.