Description

3-Furancarboxaldehyde, 5-(Difluoromethyl)- (9Ci) is a specialized furan-based aldehyde building block featuring a difluoromethyl substituent, offering unique electronic and steric properties for advanced synthesis. This compound is valued for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the difluoromethyl group can significantly influence bioavailability and metabolic stability. It is primarily sought by research and development chemists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the difluoromethyl moiety can enhance biological activity and environmental profile.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers, liquid crystals, or organic electronic materials with tailored properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Flavor & Fragrance Chemistry: Potential use as a high-value intermediate for creating novel synthetic aroma chemicals with unique organoleptic properties.
• Academic & Contract Research: Essential for methodological development and exploratory organic synthesis in university and CRO laboratory settings.

Basic Information

Item	Detail
Product Name	3-Furancarboxaldehyde, 5-(Difluoromethyl)- (9Ci)
CAS No.	153026-75-6
Molecular Formula	C6H4F2O2
Molecular Weight	146.09 g/mol
Synonyms	5-(Difluoromethyl)furan-3-carboxaldehyde; 5-(Difluoromethyl)-3-furaldehyde; 3-Furaldehyde, 5-(difluoromethyl)-; 5-Difluoromethyl-3-furancarboxaldehyde; 5-(Difluoromethyl)-3-furancarbaldehyde; Difluoromethylfuraldehyde; 153026-75-6 (CAS)
EINECS	Contact for details

Quality Control

Every batch of 3-Furancarboxaldehyde, 5-(Difluoromethyl)- is produced and controlled under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, GC, NMR, and IR is supplied with each shipment, ensuring full traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.