Description

2-(4-Fluoro-Phenyl)-Oxazole-4-Carbaldehyde is a versatile fluorinated oxazole derivative, a key heterocyclic building block prized for its unique chemical reactivity. This compound matters for its role as a crucial intermediate in the synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and advanced materials. Pharmaceutical researchers, agrochemical developers, and specialty chemical manufacturers need it to construct novel compounds with targeted biological or functional properties.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated oxazole scaffold.
• Material Science: Serves as a building block for organic light-emitting diodes (OLEDs), liquid crystals, and other functional materials requiring specific electronic properties.
• Chemical Synthesis: Employed in organic chemistry as a versatile aldehyde-containing heterocycle for condensation reactions, cyclizations, and the creation of combinatorial libraries.
• Bioconjugation & Probe Development: The aldehyde functional group allows for site-specific labeling of proteins, peptides, and other biomolecules for diagnostic and research applications.

Basic Information

Product Name	2-(4-Fluoro-Phenyl)-Oxazole-4-Carbaldehyde
CAS No.	152940-51-7
Molecular Formula	C10H6FNO2
Molecular Weight	191.16 g/mol
Synonyms	4-Fluoro-2-(4-fluorophenyl)-1,3-oxazole-5-carbaldehyde; 2-(4-Fluorophenyl)-1,3-oxazole-4-carboxaldehyde; 4-Fluorophenyl-oxazole-4-carboxaldehyde; 2-(p-Fluorophenyl)oxazole-4-carbaldehyde; 152940-51-7; 4-Fluoro-2-(4-fluorophenyl)oxazole-5-carbaldehyde; Oxazole, 2-(4-fluorophenyl)-4-formyl-
EINECS	Contact for details

Quality Control

Our 2-(4-Fluoro-Phenyl)-Oxazole-4-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.