Description

(2,2,2-Trifluoroethoxy)Difluoroacetic Acid is a specialized fluorinated organic acid building block of significant interest in advanced chemical synthesis. Its unique structure, featuring both a trifluoroethoxy and a difluoroacetic acid moiety, makes it a valuable precursor for introducing fluorine-containing groups into target molecules. This compound is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, potentially enhancing metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, pesticides, and fungicides with improved efficacy.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized fluorinated ligands used in catalysis and material science.
• Advanced Material Research: Employed in the synthesis of fluorinated polymers, surfactants, or liquid crystals with unique properties.
• Organic Synthesis Building Block: Provides a versatile handle for introducing fluorine atoms and acid functionality in complex molecule construction.

Basic Information

Product Name	(2,2,2-Trifluoroethoxy)Difluoroacetic Acid
CAS No.	152538-73-3
Molecular Formula	C4H3F5O3
Molecular Weight	194.06 g/mol
Synonyms	2,2-Difluoro-2-(2,2,2-trifluoroethoxy)acetic Acid; Difluoro(2,2,2-trifluoroethoxy)acetic Acid; α,α-Difluoro-ω,ω,ω-trifluoroethoxyacetic Acid; 2-(Trifluoroethoxy)-2,2-difluoroacetic Acid; TFEDFA; TFE-DFA; (TFE)Difluoroacetic Acid
EINECS	Contact for details

Quality Control

Our (2,2,2-Trifluoroethoxy)Difluoroacetic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including assay (HPLC), identity confirmation (IR, NMR), and impurity profiling, to ensure it meets the high-purity standards required for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Due to its nature as a strong acid/organic solvent, appropriate secondary containment is recommended. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.