Description

6-o-(2-Hydroxypropyl)Cyclomaltoheptaose is a chemically modified derivative of β-cyclodextrin, specifically designed to enhance solubility and complexation properties. This modification is critical for improving the bioavailability and stability of active ingredients in advanced formulations. It is an essential excipient for pharmaceutical, nutraceutical, and specialty chemical manufacturers seeking to solve solubility challenges and create controlled-release systems.

Application

• Pharmaceutical Solubility & Bioavailability Enhancer: Used to form inclusion complexes with poorly water-soluble active pharmaceutical ingredients (APIs) to improve their dissolution rate and absorption.
• Flavor & Fragrance Encapsulation: Acts as a molecular encapsulant in food and cosmetic products to protect volatile compounds, mask unpleasant tastes, and control release.
• Stabilizer for Sensitive Compounds: Protects ingredients prone to oxidation, light degradation, or hydrolysis by forming protective host-guest complexes.
• Catalyst & Reaction Media Component: Employed in green chemistry applications as a supramolecular catalyst or as a component of reaction media to influence selectivity and yield.
• Analytical Chemistry Reagent: Serves as a chiral selector in capillary electrophoresis and chromatographic methods for the separation of enantiomers.
• Advanced Material Synthesis: Used as a building block or template in the synthesis of functional polymers, nanomaterials, and sensor systems.

Basic Information

Product Name	6-o-(2-Hydroxypropyl)Cyclomaltoheptaose
CAS No.	152203-30-0
Molecular Formula	C63H112O42
Molecular Weight	1541.55 g/mol
Synonyms	2-Hydroxypropyl-β-cyclodextrin (HP-β-CD); Hydroxypropyl Betadex; Heptakis(2-O-hydroxypropyl)-β-cyclodextrin; HPBCD; 6-O-(2-Hydroxypropyl)-β-cyclodextrin; Kleptose® HPB; Encapsin® HPB; (2-Hydroxypropyl)-β-cyclodextrin
EINECS	Contact for details

Quality Control

Our 6-o-(2-Hydroxypropyl)Cyclomaltoheptaose is manufactured under a quality management system and undergoes rigorous analytical testing to ensure batch-to-batch consistency and compliance with relevant standards. We provide comprehensive support for pharmaceutical development, including DMF (Drug Master File) referencing. A Certificate of Analysis (COA) detailing purity, substitution degree, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment to prevent moisture absorption and caking.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Degree of Substitution	0.6 - 0.9 (or as specified)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Microbial Limits	Meets Ph. Eur./USP criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.