Description

1-(2,4-Difluorophenyl)-2-Methylpropan-1-One CAS NO 151856-34-7 is a high-purity fluorinated aromatic ketone building block of significant importance in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its difluorophenyl moiety is leveraged to modulate biological activity and metabolic stability. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where fluorine substitution enhances efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Chemistry: Acts as a monomer or cross-linking agent for the development of specialty fluorinated polymers with unique thermal and chemical resistance.
• Chemical Research & Development: Employed in academic and industrial labs for method development, catalysis studies, and exploring new fluorination reactions.
• Fine Chemical Production: Integral to the multi-step synthesis of complex fragrance and flavor compounds requiring specific fluorinated motifs.

Basic Information

Product Name	1-(2,4-Difluorophenyl)-2-Methylpropan-1-One
CAS No.	151856-34-7
Molecular Formula	C10H10F2O
Molecular Weight	184.18 g/mol
Synonyms	2,4-Difluorophenyl isobutyl ketone; Isobutyl 2,4-difluorophenyl ketone; 2-Methyl-1-(2,4-difluorophenyl)propan-1-one; 1-(2,4-Difluorophenyl)-2-methyl-1-propanone; α,α-Dimethyl-2,4-difluoroacetophenone; 2,4-Difluoro-α,α-dimethylacetophenone; 2,4-DFPIBK; 151856-34-7
EINECS	Contact for details

Quality Control

Our 1-(2,4-Difluorophenyl)-2-Methylpropan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.