Description

3'-De(Dimethylamino)-3'-[[(2-Methoxyethoxy)Methyl]Dimethylammonio]Erythromycin 9-Oxime Chloride is a chemically modified erythromycin derivative, representing a key intermediate in the synthesis of advanced macrolide antibiotics. This compound is engineered to enhance pharmacokinetic properties and overcome bacterial resistance mechanisms, making it a critical component for pharmaceutical R&D and manufacturing. It is primarily utilized by research institutions and pharmaceutical companies developing next-generation antibacterial therapies.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel semisynthetic macrolide antibiotics, such as certain ketolides.
• Antibacterial Research: Used in biochemical and microbiological research to study structure-activity relationships (SAR) and mechanisms of action against resistant bacterial strains.
• API Development: Serves as a precursor in the development and scale-up of new Active Pharmaceutical Ingredients (APIs) targeting respiratory tract and skin infections.
• Reference Standard: Employed as a high-purity analytical standard for quality control and regulatory compliance testing in pharmaceutical production.

Basic Information

Product Name	3'-De(Dimethylamino)-3'-[[(2-Methoxyethoxy)Methyl]Dimethylammonio]Erythromycin 9-Oxime Chloride
CAS No.	151750-47-9
Molecular Formula	C40H78ClN3O15
Molecular Weight	860.52 g/mol
Synonyms	3'-De(Dimethylamino)-3'-[[(2-Methoxyethoxy)Methyl]Dimethylammonio]Erythromycin 9-Oxime Chloride; 3'-N-Desmethyl-3'-N-[(2-methoxyethoxy)methyl]azithromycin 9-oxime chloride; Erythromycin 9-oxime, 3'-de(dimethylamino)-3'-[[(2-methoxyethoxy)methyl]dimethylammonio]-, chloride; A-80556 chloride; Telithromycin intermediate; Cethromycin intermediate; ABT-773 intermediate
EINECS	Contact for details

Quality Control

Our 3'-De(Dimethylamino)-3'-[[(2-Methoxyethoxy)Methyl]Dimethylammonio]Erythromycin 9-Oxime Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical development. Certificates of Analysis (COA) detailing specific results are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.