Description

2-(Trifluoromethyl)-4H-Chromen-4-One is a high-purity fluorinated chromenone derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in the unique reactivity and physicochemical properties imparted by the trifluoromethyl group, enabling the development of novel compounds with enhanced stability and bioactivity. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to incorporate fluorinated motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in developing molecules with improved metabolic stability and membrane permeability.
• Agrochemical Research: Used in creating advanced active ingredients for crop protection agents, where the trifluoromethyl group can enhance efficacy and environmental profile.
• Material Science Precursor: Serves as a monomer or functional additive in the development of specialty polymers and advanced organic electronic materials.
• Fluorine Chemistry Research: An important reagent for studying structure-activity relationships (SAR) and the effects of fluorine substitution in heterocyclic systems.
• Ligand and Catalyst Development: Utilized in the design and synthesis of novel chiral ligands or organocatalysts for asymmetric synthesis.

Basic Information

Product Name	2-(Trifluoromethyl)-4H-Chromen-4-One
CAS No.	151668-40-5
Molecular Formula	C10H5F3O2
Molecular Weight	214.14 g/mol
Synonyms	2-(Trifluoromethyl)chromen-4-one; 4H-1-Benzopyran-4-one, 2-(trifluoromethyl)-; 2-Trifluoromethyl-4-chromone; 2-Trifluoromethylchromone; 2-(Trifluoromethyl)-4-chromone; 2-(Trifluoromethyl)-4H-1-benzopyran-4-one
EINECS	Contact for details

Quality Control

Every batch of 2-(Trifluoromethyl)-4H-Chromen-4-One is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles by techniques such as HPLC, NMR, and GC-MS is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.