Description

3-o-(E)-Hydroxycinnamoyl Oleanolic Acid is a specialized, semi-synthetic derivative of the naturally occurring pentacyclic triterpenoid, oleanolic acid. This compound is valued for its enhanced bioactivity and serves as a critical high-purity reference standard and key intermediate in advanced pharmaceutical and nutraceutical research. It is primarily sought by R&D and quality control laboratories in the pharmaceutical, cosmetic, and dietary supplement industries for developing novel therapeutic agents and analytical methods.

Application

• Pharmaceutical Reference Standard: Used for the identification, assay, and impurity profiling of oleanolic acid-based drug candidates and finished products in HPLC and LC-MS analysis.
• Bioactive Ingredient R&D: Serves as a key intermediate in the synthesis of novel compounds for investigating anti-inflammatory, hepatoprotective, and anti-cancer activities.
• Nutraceutical Formulation: Employed in the development of high-end dietary supplements targeting metabolic and liver health.
• Cosmeceutical Applications: Incorporated into research for advanced skincare formulations aimed at anti-aging and skin barrier enhancement.
• Academic & Institutional Research: Utilized in university and contract research organizations (CROs) for pharmacological and biochemical studies.

Basic Information

Product Name	3-o-(E)-Hydroxycinnamoyl Oleanolic Acid
CAS No.	151334-06-4
Molecular Formula	C39H54O5
Molecular Weight	602.85 g/mol
Synonyms	3-O-(E)-p-Coumaroyl Oleanolic Acid; Olean-12-en-28-oic acid, 3-[[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-, (3β)-; 3β-[[(2E)-3-(4-Hydroxyphenyl)acryloyl]oxy]olean-12-en-28-oic Acid; 3-O-Caffeoyl Oleanolic Acid (common misnomer); 3-O-p-Coumaroyloleanolic Acid; (3β)-3-[[(2E)-3-(4-Hydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]olean-12-en-28-oic Acid
EINECS	Contact for details

Quality Control

Our 3-o-(E)-Hydroxycinnamoyl Oleanolic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or quality specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.