Description

Cyclopropanecarboxylic Acid, 2,2-Difluoro-, Ethyl Ester (9Ci) is a high-value fluorinated organic building block, prized for its unique cyclopropane ring structure and difluoro substitution. This compound is critical for introducing conformational rigidity and fluorine atoms into target molecules, which can dramatically alter their physical, chemical, and biological properties. It is primarily sought by research chemists and process development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorinated cyclopropane moiety can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced materials with tailored surface properties.
• Fluorine Chemistry Research: An essential reagent for academic and industrial research exploring new methodologies in organofluorine chemistry and asymmetric synthesis.
• Liquid Crystal & OLED Materials: Employed in the synthesis of fluorinated components for electronic display technologies and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: Acts as an electrophilic partner in various metal-catalyzed cross-coupling reactions to construct complex molecular architectures.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 2,2-Difluoro-, Ethyl Ester (9Ci)
CAS No.	151324-64-0
Molecular Formula	C6H8F2O2
Molecular Weight	150.12 g/mol
Synonyms	Ethyl 2,2-Difluorocyclopropanecarboxylate; 2,2-Difluorocyclopropanecarboxylic Acid Ethyl Ester; Ethyl 2,2-Difluorocyclopropane-1-carboxylate; 1-Carbethoxy-2,2-difluorocyclopropane; 151324-64-0; Ethyl difluorocyclopropanecarboxylate; 2,2-Difluoro-1-cyclopropanecarboxylic acid, ethyl ester
EINECS	Contact for details

Quality Control

Every batch of Cyclopropanecarboxylic Acid, 2,2-Difluoro-, Ethyl Ester is produced and analyzed under strict quality management protocols to ensure consistency and purity for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.