Description

1-(2-Chlorophenyl)Cyclobutanecarboxylic Acid is a versatile and high-purity organic building block characterized by its unique cyclobutane ring fused with a chlorinated aromatic system. This compound is of significant commercial importance as a key synthetic intermediate in the development of advanced pharmaceutical compounds and agrochemicals. It is primarily utilized by research institutions and industrial manufacturers in the fine chemical, pharmaceutical, and agrochemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, leveraging its chlorophenyl moiety for biological activity.
• Material Science Research: Acts as a monomer or building block for developing specialty polymers and liquid crystals with tailored properties.
• Organic Synthesis & Catalysis: Employed in academic and industrial R&D for studying cyclobutane ring reactions and developing new catalytic methodologies.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in regulatory and manufacturing environments.

Basic Information

Product Name	1-(2-Chlorophenyl)Cyclobutanecarboxylic Acid
CAS No.	151157-45-8
Molecular Formula	C11H11ClO2
Molecular Weight	210.66 g/mol
Synonyms	2-Chloro-α-cyclobutanebenzenepropanoic acid; 1-(2-Chlorophenyl)cyclobutane-1-carboxylic acid; Cyclobutanecarboxylic acid, 1-(2-chlorophenyl)-; 2-Chlorophenylcyclobutanecarboxylic acid; 1-(o-Chlorophenyl)cyclobutanecarboxylic acid; (2-Chlorophenyl)cyclobutanecarboxylic acid; 151157-45-8; CCRIS 9378
EINECS	Contact for details

Quality Control

Our 1-(2-Chlorophenyl)Cyclobutanecarboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure it meets the high-purity standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.