Description

3A,4,7,7A-Tetrahydro-2-Phenyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Isoindole-1,3(2H)-Dione is a specialized organic building block featuring a phthalimide core functionalized with a pinacol boronate ester group. This compound matters as a versatile intermediate for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for synthesizing novel active ingredients and advanced materials.

Application

• Key intermediate in pharmaceutical research for the synthesis of drug candidates and active pharmaceutical ingredients (APIs).
• Building block for Suzuki-Miyaura cross-coupling reactions to create biaryl and conjugated systems.
• Precursor in agrochemical development for novel herbicides, fungicides, and insecticides.
• Monomer or functionalizing agent in the synthesis of advanced organic materials, such as OLEDs and polymers.
• Used in academic and industrial R&D for exploring new chemical spaces and reaction methodologies.
• Intermediate for creating molecular probes and labeled compounds for biological studies.

Basic Information

Product Name	3A,4,7,7A-Tetrahydro-2-Phenyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Isoindole-1,3(2H)-Dione
CAS No.	151075-25-1
Molecular Formula	C22H26BNO4
Molecular Weight	379.26 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-phenylisoindoline-1,3-dione; 2-Phenyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoindoline-1,3-dione; 1H-Isoindole-1,3(2H)-dione, 3a,4,7,7a-tetrahydro-2-phenyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; Pinacol (2-phenyl-1,3-dioxoisoindolin-5-yl)boronate; Boronic acid, B-(2-phenyl-1,3-dihydro-1,3-dioxo-4H-isoindol-5-yl)-, pinacol ester
EINECS	Contact for details

Quality Control

Our 3A,4,7,7A-Tetrahydro-2-Phenyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Isoindole-1,3(2H)-Dione is manufactured under strict quality protocols. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process chemistry. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Recommended storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.