Description

n-Boc-(S)-2-Amino-1-Butanol, 96% is a protected chiral amino alcohol building block of significant importance in synthetic organic chemistry. Its core value lies in providing a versatile, enantiomerically pure scaffold for the construction of complex molecules, where the Boc (tert-butoxycarbonyl) group offers orthogonal protection for the amine functionality. This compound is essential for researchers and process chemists in the pharmaceutical and fine chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs), chiral ligands, and peptidomimetics. The specified purity of 96% ensures reliable performance in demanding synthetic sequences.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting the central nervous system and infectious diseases.
• Peptidomimetic & Peptide Chemistry: Used to incorporate non-natural amino acid residues or to create backbone-modified peptide analogs with enhanced metabolic stability.
• Chiral Auxiliary & Ligand Synthesis: Serves as a precursor for the development of chiral catalysts, ligands for asymmetric catalysis, and auxiliaries for diastereoselective reactions.
• Fine Chemical & Agrochemical Synthesis: Employed in the research and production of specialty chemicals, including advanced agrochemicals and performance materials requiring specific stereochemistry.
• Academic & Process R&D: A valuable reagent for methodological development in organic synthesis and for scaling up chiral synthetic routes in process chemistry.

Basic Information

Product Name	n-Boc-(S)-2-Amino-1-Butanol, 96%
CAS No.	150736-72-4
Molecular Formula	C9H19NO3
Molecular Weight	189.25 g/mol
Synonyms	(S)-2-[(tert-Butoxycarbonyl)amino]-1-butanol; (S)-2-(Boc-amino)-1-butanol; (S)-N-Boc-2-amino-1-butanol; tert-Butyl (S)-(1-hydroxybutan-2-yl)carbamate; (S)-N-(tert-Butoxycarbonyl)-2-amino-1-butanol; Boc-L-homoalaninol; (S)-2-Amino-1-butanol, N-Boc-protected
EINECS	Contact for details

Quality Control

Our n-Boc-(S)-2-Amino-1-Butanol, 96% is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the specified 96% minimum purity and enantiomeric excess. Certificates of Analysis (COA) detailing identity (IR, NMR), assay, and impurity profiles are available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation by atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 96.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.