Description

3'-Bromo-4',2,2,2-Tetrafluoroacetophenone 98 is a high-purity fluorinated aromatic ketone building block, essential for advanced organic synthesis. Its value lies in the strategic combination of bromine and fluorine substituents, which enable precise functionalization and modulate the electronic properties of target molecules. This compound is primarily needed by researchers and process chemists in the pharmaceutical and agrochemical industries for developing new active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorine-containing drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic electronic materials, contributing to improved performance in displays and lighting.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial R&D exploring new fluorination methodologies and the effects of fluorine substitution.
• Specialty Polymer Monomer: Can be utilized to synthesize fluorinated polymers with unique thermal, chemical, and surface properties.

Basic Information

Item	Detail
Product Name	3'-Bromo-4',2,2,2-Tetrafluoroacetophenone 98
CAS No.	150698-74-1
Molecular Formula	C8H3BrF4O
Molecular Weight	270.99 g/mol
Synonyms	1-(3-Bromo-4-fluorophenyl)-2,2,2-trifluoroethanone; 3'-Bromo-4'-fluoro-2,2,2-trifluoroacetophenone; α,α,α-Trifluoro-3-bromo-4-fluoroacetophenone; 2,2,2-Trifluoro-1-(3-bromo-4-fluorophenyl)ethanone; 3-Bromo-4-fluorophenyl trifluoromethyl ketone; 1-(3-Bromo-4-fluorophenyl)-2,2,2-trifluoro-1-ethanone; 150698-74-1
EINECS	Contact for details

Quality Control

Our 3'-Bromo-4',2,2,2-Tetrafluoroacetophenone 98 is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. The compound is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.