Description

D-Allothreonine, 4-Fluoro-, Ethyl Ester (9Ci) is a fluorinated amino acid ester derivative, a high-value chiral building block in advanced organic synthesis. Its core value lies in introducing the unique 4-fluoro-allothreonine moiety into complex molecules, enabling precise modulation of biological activity and physicochemical properties. This compound is essential for researchers and manufacturers in pharmaceutical development, particularly for creating novel peptide-based therapeutics, protease inhibitors, and diagnostic agents.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of fluorinated peptide drugs and enzyme inhibitors.
• Proteomics Research: Used in the study of enzyme mechanisms and protein structure-activity relationships (SAR).
• Medicinal Chemistry: Incorporation into candidate molecules to enhance metabolic stability, bioavailability, and binding affinity.
• Chemical Biology: A tool compound for labeling and probing biological systems using fluorine as a spectroscopic handle.
• Agrochemical Synthesis: Potential intermediate in the design of advanced, bioactive compounds.

Basic Information

Product Name	D-Allothreonine, 4-Fluoro-, Ethyl Ester (9Ci)
CAS No.	150672-43-8
Molecular Formula	C7H12FNO3
Molecular Weight	177.17 g/mol
Synonyms	Ethyl (2S,3R)-2-amino-3-fluoro-4-ethoxy-4-oxobutanoate; D-4-Fluoroallothreonine Ethyl Ester; (2S,3R)-2-Amino-3-fluorobutanoic Acid 4-Ethyl Ester; 4-Fluoro-D-allothreonine Ethyl Ester; (2S,3R)-Ethyl 2-amino-3-fluorobutanoate; 150672-43-8; D-allo-Thr(4-F)-OEt; Fluorinated D-allothreonine Ester
EINECS	Contact for details

Quality Control

We supply D-Allothreonine, 4-Fluoro-, Ethyl Ester (9Ci) to high-purity standards suitable for research and development. Our products undergo rigorous quality testing, including chiral purity analysis, to ensure batch-to-batch consistency and compliance with customer specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), and chiral excess is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.