Description

Methyl 1,2,3,4-Tetra-o-Isobutyryl-B-D-Glucopyranuronate is a key protected sugar derivative, specifically a methyl glucuronate esterified with isobutyryl groups. This compound serves as a crucial synthetic intermediate, offering a protected scaffold for the controlled introduction of glucuronic acid moieties in complex molecule synthesis. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and fine chemical industries for the development of novel therapeutics, prodrugs, and advanced biomaterials.

Application

• Pharmaceutical Intermediate: Serves as a vital building block for the synthesis of glycosylated drugs, prodrugs, and targeted therapeutic agents.
• Glycoconjugate Synthesis: Used in the preparation of complex glycoconjugates for biological studies and vaccine development.
• Medicinal Chemistry Research: Acts as a precursor for creating glucuronide derivatives to study drug metabolism and detoxification pathways.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes to investigate carbohydrate-protein interactions.
• Fine Chemical Synthesis: Utilized as a specialized chiral synthon in multi-step organic synthesis for high-value compounds.
• Polymer & Material Science: Can be incorporated into polymers to create biodegradable or bioactive materials with specific properties.

Basic Information

Product Name	Methyl 1,2,3,4-Tetra-o-Isobutyryl-B-D-Glucopyranuronate
CAS No.	150607-94-6
Molecular Formula	C27H42O12
Molecular Weight	558.62 g/mol
Synonyms	Methyl 2,3,4-Tri-O-isobutyryl-β-D-glucopyranosiduronic Acid 1-Isobutyrate; Methyl β-D-Glucopyranosiduronic Acid 1,2,3,4-Tetraisobutyrate; 1,2,3,4-Tetra-O-isobutyryl-β-D-glucopyranuronic Acid Methyl Ester; Methyl Tetra-O-isobutyryl-β-D-glucuronate; Glucuronic Acid Methyl Ester Tetra-Isobutyrate; β-D-Glucopyranuronic Acid, Methyl Ester, Tetra-Isobutyrate
EINECS	Contact for details

Quality Control

Our Methyl 1,2,3,4-Tetra-o-Isobutyryl-B-D-Glucopyranuronate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Specific Rotation	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.