Description

Cyclopropyl 2-Fluorobenzyl Ketone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the cyclopropyl and fluorobenzyl motifs are key pharmacophores. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate its unique structural features into new molecular entities.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antiviral compounds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorinated aromatic ring can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the development of novel organic electronic materials and liquid crystals, leveraging its rigid, fluorinated structure.
• Chemical Biology Probes: Utilized as a scaffold for designing molecular probes and inhibitors to study enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	Cyclopropyl 2-Fluorobenzyl Ketone
CAS No.	150322-73-9
Molecular Formula	C11H11FO
Molecular Weight	178.20 g/mol
Synonyms	1-Cyclopropyl-2-(2-fluorophenyl)ethanone; 2-Fluorobenzyl Cyclopropyl Ketone; (2-Fluorophenyl)(cyclopropyl)methanone; Cyclopropyl(o-fluorophenyl)methanone; 2-Fluoro-α-cyclopropylbenzeneacetaldehyde; (2-Fluorobenzyl)cyclopropyl ketone; α-Cyclopropyl-2-fluoroacetophenone
EINECS	Contact for details

Quality Control

Our Cyclopropyl 2-Fluorobenzyl Ketone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.