Description

2-Bromobenzylboronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron building block. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and advanced materials sectors to introduce the 2-bromobenzyl moiety into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in constructing novel herbicides, fungicides, and insecticides that require specific benzyl-substituted structures.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands and organometallic catalysts.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where precise molecular engineering is critical.
• Chemical Biology Probes: Useful for synthesizing tagged molecules and probes for biochemical and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and small-molecule libraries.

Basic Information

Product Name	2-Bromobenzylboronic Acid Pinacol Ester
CAS No.	149989-79-7
Molecular Formula	C₁₃H₁₈BBrO₂
Molecular Weight	297.00 g/mol
Synonyms	2-Bromobenzylboronic acid pinacol ester; (2-Bromobenzyl)boronic acid pinacol ester; 2-Bromobenzylboronic acid, pinacol cyclic ester; 4,4,5,5-Tetramethyl-2-(2-bromobenzyl)-1,3,2-dioxaborolane; 2-(2-Bromobenzyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol (2-bromobenzyl)boronate; (2-Bromophenylmethyl)boronic acid pinacol ester.
EINECS	Contact for details

Quality Control

Our 2-Bromobenzylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and consistent performance in sensitive coupling reactions. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to prevent hydrolysis and maintain reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.