Description

1-Bromo-3-Bromomethyl-2-Fluorobenzene is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile intermediate, enabling the precise introduction of bromine and fluorine substituents into complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel materials.

Application

• Key pharmaceutical intermediate for the synthesis of fluorinated drug candidates, particularly in kinase inhibitor and CNS-active molecule research.
• Versatile building block in agrochemical synthesis for creating novel herbicides and pesticides with enhanced properties.
• Precursor for liquid crystal materials and other specialty fluorinated polymers used in electronics and display technologies.
• Used in cross-coupling reactions (e.g., Suzuki, Heck) due to the reactivity of its bromine substituents.
• Intermediate in the development of PET (Positron Emission Tomography) tracers and other diagnostic agents.
• Starting material for organic synthesis research in academic and industrial laboratories exploring new fluorination methodologies.

Basic Information

Product Name	1-Bromo-3-Bromomethyl-2-Fluorobenzene
CAS No.	149947-16-0
Molecular Formula	C7H5Br2F
Molecular Weight	267.92 g/mol
Synonyms	2-Fluoro-1,3-dibromomethylbenzene; 3-Bromomethyl-1-bromo-2-fluorobenzene; 2-Fluoro-α,α'-dibromo-m-xylene; 1,3-Bis(bromomethyl)-2-fluorobenzene; 2-Fluorobenzene-1,3-diyldimethylene dibromide; m-Xylene-α,α'-dibromo-2-fluoro-; (2-Fluoro-1,3-phenylene)bis(methylene) dibromide
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-Bromomethyl-2-Fluorobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.