Description

(E)-Methyl 3-(4-Bromo-2-Fluorophenyl)Acrylate CAS NO 149947-09-1 is a high-purity, versatile chemical intermediate characterized by its distinct aromatic halogen substitution and acrylate ester functionality. This compound is essential for facilitating complex molecular transformations in advanced synthetic chemistry, offering a critical building block for creating more complex target molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of active pharmaceutical ingredients (APIs), particularly for molecules requiring a halogenated phenylacrylic acid scaffold.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Liquid Crystal & OLED Material Research: Used in the synthesis of advanced organic electronic materials and liquid crystal compounds due to its rigid, conjugated core.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions, enabling the construction of complex biaryl systems.
• Polymer Chemistry: Acts as a monomer or co-monomer for specialty polymers, imparting specific properties like UV stability or modified solubility.
• Organic Synthesis & Academic Research: A valuable reagent for constructing complex organic molecules in medicinal chemistry and material science research programs.

Basic Information

Product Name	(E)-Methyl 3-(4-Bromo-2-Fluorophenyl)Acrylate
CAS No.	149947-09-1
Molecular Formula	C10H8BrFO2
Molecular Weight	259.07 g/mol
Synonyms	Methyl (2E)-3-(4-Bromo-2-fluorophenyl)-2-propenoate; (E)-Methyl 3-(4-Bromo-2-fluorophenyl)propenoate; trans-Methyl 3-(4-Bromo-2-fluorophenyl)acrylate; Methyl (E)-3-(4-Bromo-2-fluorophenyl)acrylate; 4-Bromo-2-fluorocinnamic acid methyl ester; (E)-4-Bromo-2-fluorocinnamic acid methyl ester; 2-Propenoic acid, 3-(4-bromo-2-fluorophenyl)-, methyl ester, (2E)-
EINECS	Contact for details

Quality Control

Our (E)-Methyl 3-(4-Bromo-2-Fluorophenyl)Acrylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.