Description

Cyclopropanecarboxylic Acid, 1-Amino-2-(1-Methylethyl)-, cis- (9Ci) is a specialized chiral cyclopropane derivative, a high-value building block prized for its constrained three-dimensional structure. This compound is critical for introducing unique steric and electronic properties into target molecules, enabling the development of advanced materials and pharmaceuticals. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications in medicinal chemistry, asymmetric synthesis, and ligand design.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug discovery programs.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the cyclopropane ring can enhance biological activity and environmental stability.
• Asymmetric Catalysis: Serves as a precursor for chiral ligands and organocatalysts, facilitating enantioselective transformations in fine chemical synthesis.
• Advanced Material Synthesis: Incorporated into polymers and specialty chemicals to modify physical properties such as rigidity, thermal stability, or optical activity.
• Chemical Biology & Proteomics: Utilized as a scaffold or labeling agent in the design of molecular probes and enzyme inhibitors for biochemical research.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 1-Amino-2-(1-Methylethyl)-, cis- (9Ci)
CAS No.	149811-53-0
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	cis-1-Amino-2-isopropylcyclopropanecarboxylic acid; (1S,2S)-1-Amino-2-(propan-2-yl)cyclopropane-1-carboxylic acid; L-2-Amino-3-cyclopropylbutanoic acid derivative; 1-Amino-2-isopropylcyclopropanecarboxylic acid, cis-; Cyclopropanecarboxylic acid, 1-amino-2-(1-methylethyl)-, (1S,2S)-; cis-2-Amino-3-cyclopropylbutyric acid; A building block for constrained peptides.
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 1-Amino-2-(1-Methylethyl)-, cis- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.