Description

4-Nitro-trans-β-Styrylboronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and versatile building block for organic synthesis. Its core value lies in its role as a key precursor in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. This compound is essential for researchers and manufacturers in pharmaceutical R&D, agrochemical development, and materials science, particularly for creating novel compounds with nitro-substituted styryl frameworks.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring a nitro-styryl moiety.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a key boronic ester reagent for forming carbon-carbon bonds, enabling the synthesis of complex biaryl and conjugated systems.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its functionalized aromatic structure.
• Material Science & OLED Development: Acts as a precursor for creating organic light-emitting diode (OLED) materials and other advanced functional materials with specific electronic properties.
• Chemical Biology & Probe Development: Utilized in the design and synthesis of molecular probes and bio-conjugates for studying biological processes.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and for exploring new synthetic pathways.

Basic Information

Item	Details
Product Name	4-Nitro-trans-β-Styrylboronic Acid Pinacol Ester
CAS No.	149777-86-6
Molecular Formula	C18H18BNO4
Molecular Weight	323.15 g/mol
Synonyms	trans-4-Nitrostyrylboronic Acid Pinacol Ester; (E)-4-Nitrostyrylboronic Acid Pinacol Ester; 4-Nitro-β-styrylboronic Acid Pinacol Ester; 2-(4-Nitrovinylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol (E)-4-Nitrostyrylboronate; Boronic acid, B-[(1E)-2-(4-nitrophenyl)ethenyl]-, 1,1-dimethylethyl ester; 149777-86-6
EINECS	Contact for details

Quality Control

Our 4-Nitro-trans-β-Styrylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.