Description

2-Methoxy-trans-β-Styrylboronic Acid Pinacol Ester is a high-value, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a key Suzuki-Miyaura cross-coupling partner, enabling the efficient construction of complex biaryl and conjugated systems. It is primarily utilized by researchers and process chemists in pharmaceutical development, agrochemical synthesis, and advanced materials science for creating novel molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing methoxy-substituted stilbene or biphenyl cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators that require specific aryl-aryl linkages.
• Material Science Research: Employed in the creation of organic semiconductors, liquid crystals, and advanced polymers where controlled conjugation and specific substitution patterns are critical.
• Cross-Coupling Reactions: A reliable reagent for Suzuki-Miyaura cross-coupling with various aryl/vinyl halides or triflates, prized for its stability and reactivity.
• Chemical Biology Probes: Used in the development of molecular probes and tags for studying biological processes, leveraging the bioorthogonal nature of the boronic ester group.
• Organic Synthesis Scaffold: Serves as a versatile intermediate for further functionalization, including deprotection to the free boronic acid or transesterification.

Basic Information

Product Name	2-Methoxy-trans-β-Styrylboronic Acid Pinacol Ester
CAS No.	149777-81-1
Molecular Formula	C₁₇H₂₅BO₃
Molecular Weight	288.19 g/mol
Synonyms	trans-2-Methoxystyrylboronic Acid Pinacol Ester; (E)-2-Methoxystyrylboronic Acid Pinacol Ester; 2-Methoxy-β-styrylboronic Acid Pinacol Ester; (2-Methoxyethenyl)benzeneboronic Acid Pinacol Ester; Pinacol (E)-2-(2-Methoxyvinyl)phenylboronate; B-(2-[(E)-2-Methoxyethenyl]phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2-Methoxy-trans-β-Styrylboronic Acid Pinacol Ester is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and isomeric integrity. Certificates of Analysis (COA) with full characterization data are provided to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and light-sensitive nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Isomeric Purity (HPLC)	≥98.0% (trans-isomer)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.