Description

Heptanoic Acid, 2-Amino-3-Fluoro-, [R-(R*,S*)]- (9Ci) is a high-purity, stereochemically defined fluorinated amino acid derivative, serving as a sophisticated chiral building block in advanced organic synthesis. Its value lies in the precise introduction of fluorine and amino functionality into a heptanoic acid backbone, enabling the modulation of biological activity and physicochemical properties in target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly for applications requiring specific stereochemistry and fluorination.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting metabolic diseases, CNS disorders, and oncology.
• Agrochemical Synthesis: Used in the creation of advanced, fluorinated herbicides, fungicides, and plant growth regulators where the fluorine atom enhances bioavailability and environmental stability.
• Peptidomimetics & Bioactive Molecule Design: Incorporated into peptide analogs and other bioactive compounds to improve metabolic stability, membrane permeability, and binding affinity.
• Chemical Biology Probes: Serves as a building block for fluorescent tags, enzyme inhibitors, and other molecular probes used in biochemical and pharmacological research.
• Material Science Research: Potential monomer or modifier for creating specialized polymers with unique surface properties or self-assembly characteristics.
• Asymmetric Catalysis Ligand Precursor: Can be utilized to synthesize novel chiral ligands or organocatalysts for enantioselective transformations.

Basic Information

Product Name	Heptanoic Acid, 2-Amino-3-Fluoro-, [R-(R*,S*)]- (9Ci)
CAS No.	149560-56-5
Molecular Formula	C7H14FNO2
Molecular Weight	163.19 g/mol
Synonyms	(2R,3S)-2-Amino-3-fluoroheptanoic acid; (2R,3S)-3-Fluoro-2-aminohaptanoic acid; 2-Amino-3-fluoroheptanoic acid, (2R,3S)-; 2-Amino-3-fluoroheptanoic acid (stereoisomer); DL-threo-3-Fluoro-2-aminohaptanoic acid (relative configuration); Fluorinated C7 Amino Acid; FAH; Heptanoic acid, 2-amino-3-fluoro-, (2R,3S)-
EINECS	Contact for details

Quality Control

Our production of Heptanoic Acid, 2-Amino-3-Fluoro-, [R-(R*,S*)]- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is fully characterized and tested against rigorous in-house specifications, with a focus on chiral purity, chemical identity, and impurity profile. A comprehensive Certificate of Analysis (COA) detailing results for assay, enantiomeric excess, and related substances is provided with every shipment. Our quality system supports development and cGMP-grade production for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.