Description

3-n-Boc-3-(3,4-Methylenedioxyphenyl)Propionic Acid is a protected carboxylic acid derivative featuring a piperonyl (3,4-methylenedioxyphenyl) moiety, serving as a crucial synthetic intermediate in advanced organic chemistry. This compound matters because it provides a versatile building block for constructing complex molecules, particularly in pharmaceutical research where the Boc (tert-butoxycarbonyl) group offers orthogonal protection for amine functionalities. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of complex drug candidates, particularly those targeting neurological and psychiatric disorders.
• Peptidomimetic Research: Used to incorporate the piperonyl pharmacophore into peptide backbones to enhance stability and biological activity.
• Protease Inhibitor Development: Serves as a precursor for inhibitors where the methylenedioxyphenyl group is a key binding motif.
• Agrochemical Synthesis: Intermediate in the creation of novel pesticides and herbicides that leverage its specific aromatic structure.
• Ligand and Catalyst Preparation: Useful for synthesizing chiral ligands or metal-organic frameworks (MOFs) for asymmetric catalysis.
• Academic & Discovery Chemistry: Employed in medicinal chemistry programs for library synthesis and structure-activity relationship (SAR) studies.

Basic Information

Product Name	3-n-Boc-3-(3,4-Methylenedioxyphenyl)Propionic Acid
CAS No.	149520-06-9
Molecular Formula	C15H18O6
Molecular Weight	294.30 g/mol
Synonyms	3-(Boc-amino)-3-(3,4-methylenedioxyphenyl)propanoic acid; 3-[(tert-Butoxycarbonyl)amino]-3-(1,3-benzodioxol-5-yl)propanoic acid; 3-(tert-Butoxycarbonylamino)-3-(benzo[d][1,3]dioxol-5-yl)propanoic acid; Boc-3,4-(Methylenedioxy)phenylalanine derivative; 3-(Boc-amino)-3-(piperonyl)propionic acid; N-Boc-3-(3,4-Methylenedioxyphenyl)alanine; 3-Amino-3-(3,4-methylenedioxyphenyl)propionic acid N-Boc derivative
EINECS	Contact for details

Quality Control

Our 3-n-Boc-3-(3,4-Methylenedioxyphenyl)Propionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure compliance with research and development standards. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.