Description

Methyl 2-Acetamido-4,6-Di-o-Acetyl-2,3-Dideoxy-3-Fluoromannopyranoside CAS NO 149513-97-3 is a fluorinated carbohydrate derivative, specifically a fluorinated mannose analog, designed for advanced synthetic and medicinal chemistry applications. This compound is a critical building block for the development of novel glycosidase inhibitors, antiviral agents, and fluorinated glycoconjugates. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions focused on carbohydrate chemistry, glycobiology, and drug discovery.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated nucleoside analogs and antiviral drugs targeting viral glycosidases.
• Glycobiology Research: Used as a probe or precursor in studying carbohydrate-protein interactions, enzyme mechanisms, and metabolic pathways involving fluorosugars.
• Glycosidase Inhibitor Development: Serves as a core structure for creating potent and selective inhibitors of glycoside hydrolase enzymes.
• Fluorinated Glycoconjugate Synthesis: Enables the preparation of stable, fluorinated analogs of oligosaccharides and glycoproteins for diagnostic and therapeutic applications.
• Chemical Biology Tool: Employed in the development of activity-based probes (ABPs) and metabolic labeling agents to visualize and track glycosylation processes.
• Academic & Industrial R&D: Fundamental research in synthetic organic chemistry focused on stereoselective fluorination and carbohydrate modification.

Basic Information

Product Name	Methyl 2-Acetamido-4,6-Di-o-Acetyl-2,3-Dideoxy-3-Fluoromannopyranoside
CAS No.	149513-97-3
Molecular Formula	C13H20FNO7
Molecular Weight	321.30 g/mol
Synonyms	Methyl 2-acetamido-4,6-di-O-acetyl-2,3-dideoxy-3-fluoro-α-D-mannopyranoside; 3-Fluoro-2,3-dideoxy-4,6-di-O-acetyl-2-(acetylamino)-α-D-mannopyranoside methyl ester; 3-Fluoro-2,3-dideoxy-4,6-di-O-acetyl-2-acetamido-α-D-mannopyranoside methyl ester; Fluorinated N-acetylmannosamine derivative; 3-Fluoro-D-mannosamine derivative; Methyl 3-fluoro-2,3-dideoxy-4,6-di-O-acetyl-2-acetamido-α-D-mannopyranoside
EINECS	Contact for details

Quality Control

Our Methyl 2-Acetamido-4,6-Di-o-Acetyl-2,3-Dideoxy-3-Fluoromannopyranoside is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency suitable for research and development. Each lot undergoes comprehensive analytical characterization including HPLC, NMR (1H, 13C, 19F), and mass spectrometry. A detailed Certificate of Analysis (COA) providing purity, identity confirmation, and impurity profile is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure (1H, 13C, 19F)
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.