Description

Ethanone, 1-[(1R,3R,6S)-6-Methyl-7-Oxabicyclo[4.1.0]Hept-3-Yl]-, Rel- (9Ci) CAS NO 149251-77-4 is a high-purity, optically active bicyclic ketone derivative characterized by its specific stereochemistry. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, where its defined three-dimensional structure is essential for imparting specific biological activity or material properties. It is primarily sought after by pharmaceutical R&D and fine chemical manufacturers for the development of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring stereochemical precision.
• Asymmetric Synthesis: Used as a starting material or advanced intermediate in catalytic asymmetric reactions to construct complex molecular architectures.
• Fragrance & Flavor Chemistry: Potential precursor for the synthesis of novel, high-value odorants and flavor compounds with unique organoleptic profiles.
• Agrochemical Research: Intermediate in the development of new generation pesticides and herbicides where specific stereochemistry can influence efficacy and environmental profile.
• Material Science: Building block for specialty polymers or liquid crystals where the rigid bicyclic framework can influence material properties.
• Academic & Contract Research: Essential reagent for methodological studies in organic chemistry and for contract research organizations (CROs) serving the life sciences sector.

Basic Information

Product Name	Ethanone, 1-[(1R,3R,6S)-6-Methyl-7-Oxabicyclo[4.1.0]Hept-3-Yl]-, Rel- (9Ci)
CAS No.	149251-77-4
Molecular Formula	C10H14O2
Molecular Weight	166.22 g/mol
Synonyms	rel-(1R,3R,6S)-6-Methyl-7-oxabicyclo[4.1.0]hept-3-yl methyl ketone; 1-[(1R,3R,6S)-6-Methyl-7-oxabicyclo[4.1.0]hept-3-yl]ethanone; (1R,3R,6S)-6-Methyl-7-oxabicyclo[4.1.0]heptan-3-yl methyl ketone; Bicyclic ketone derivative; Optically active oxabicycloheptanone; Chiral acetyl oxabicycloheptane.
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and optical purity suitable for demanding synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, assay, chiral purity, and impurity profiles. We support compliance with cGMP and ISO 9001 standards for pharmaceutical and fine chemical supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.