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D-Arabino-Hexonic Acid, 2,5-Anhydro-3,6-Dideoxy-, Methyl Ester (9Ci) CAS NO 149206-62-2


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CAS No.:149206-62-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

D-Arabino-Hexonic Acid, 2,5-Anhydro-3,6-Dideoxy-, Methyl Ester (9Ci) is a specialized carbohydrate derivative and a key chiral building block in organic synthesis. Its unique deoxygenated and anhydro structure makes it a valuable intermediate for constructing complex molecules with precise stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing nucleoside analogues, antiviral agents, and other bioactive compounds.

Application

  • Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel nucleoside-based drugs, including potential antiviral and anticancer agents.
  • Fine Chemical Synthesis: Used as a versatile building block in the multi-step synthesis of complex natural products, specialty sugars, and other high-value fine chemicals.
  • Glycochemistry Research: Serves as a precursor or model compound in studies related to carbohydrate chemistry, glycosylation reactions, and the synthesis of modified sugars.
  • Bioconjugate Chemistry: Can be utilized in the development of carbohydrate-based probes, ligands, or linkers for bioconjugation and chemical biology applications.
  • Process Development: Employed in scaling up synthetic routes for active pharmaceutical ingredients (APIs) where its specific stereochemistry is required.

Basic Information

Product Name D-Arabino-Hexonic Acid, 2,5-Anhydro-3,6-Dideoxy-, Methyl Ester (9Ci)
CAS No. 149206-62-2
Molecular Formula C7H12O4
Molecular Weight 160.17 g/mol
Synonyms Methyl 2,5-anhydro-3,6-dideoxy-D-arabino-hexonate; 2,5-Anhydro-3,6-dideoxy-D-arabino-hexonic acid methyl ester; Methyl 3,6-dideoxy-2,5-anhydro-D-arabino-hexonate; D-arabino-Hexonic acid, 2,5-anhydro-3,6-dideoxy-, methyl ester; (2R,4S,5R)-Tetrahydro-4-hydroxy-2-methyl-5-(methoxycarbonyl)furan
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Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and chiral integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliant manufacturing for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Chiral Purity (Chiral HPLC) ≥ 98.0% ee
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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