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4-Acetylphenylboronicacid CAS NO 149104-47-5
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CAS No.:149104-47-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
4-Acetylphenylboronic acid is a versatile boronic acid derivative featuring both a ketone and a boronic acid functional group on an aromatic ring. This bifunctional nature makes it a highly valuable building block in modern synthetic chemistry, particularly for cross-coupling reactions like the Suzuki-Miyaura reaction. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who require precise molecular construction for developing active ingredients and advanced materials.
Application
- Pharmaceutical Intermediate: A key synthon for constructing biaryl structures found in active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling.
- Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific aromatic ketone-boronic acid motifs.
- Material Science Research: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and sensors, where the acetyl group can be further functionalized.
- Ligand and Catalyst Development: Employed in the synthesis of sophisticated ligands for transition metal catalysis and organocatalysis.
- Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes, leveraging boronic acid's affinity for diols.
- Custom Synthesis and R&D: A critical starting material for contract research organizations (CROs) and academic labs engaged in novel organic compound discovery.
Basic Information
| Product Name | 4-Acetylphenylboronic acid |
| CAS No. | 149104-47-5 |
| Molecular Formula | C8H9BO3 |
| Molecular Weight | 163.97 g/mol |
| Synonyms | (4-Acetylphenyl)boronic acid; 4-Acetylbenzeneboronic acid; p-Acetylphenylboronic acid; 1-(4-Boronophenyl)ethan-1-one; 4-Acetylbenzeneboronic Acid; 4-Acetyl-Benzeneboronic Acid; Boronic acid, B-(4-acetylphenyl)- |
| EINECS | Contact for details |
Quality Control
Our 4-Acetylphenylboronic acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere for long-term storage to maintain stability and purity.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥97.0% |
| Water Content (KF) | ≤1.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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