Description

Cyclohexanecarboxylic Acid, 3-Hydroxy-, Methyl Ester, (1S,3R)- is a high-purity chiral intermediate of significant importance in advanced organic synthesis. This compound matters for its role as a key building block in the production of complex, stereochemically defined molecules, particularly in the pharmaceutical sector. Industries that require precise chiral chemistry, such as active pharmaceutical ingredient (API) manufacturers and specialty chemical producers, rely on this material for its defined stereochemistry and consistent quality. Its utility is underscored by its application in research and development for novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used in the construction of stereocenters for fragrances, agrochemicals, and other fine chemicals requiring specific enantiomeric purity.
• Organic Synthesis Research: Serves as a valuable starting material or intermediate in academic and industrial R&D for novel organic compounds.
• Specialty Chemical Production: Employed in the manufacture of advanced materials, catalysts, or ligands where the (1S,3R) stereochemistry is essential for function.

Basic Information

Product Name	Cyclohexanecarboxylic Acid, 3-Hydroxy-, Methyl Ester, (1S,3R)-
CAS No.	149055-86-7
Molecular Formula	C9H16O3
Molecular Weight	172.22 g/mol
Synonyms	(1S,3R)-3-Hydroxycyclohexanecarboxylic Acid Methyl Ester; Methyl (1S,3R)-3-Hydroxycyclohexanecarboxylate; (1S,3R)-Methyl 3-Hydroxycyclohexanecarboxylate; trans-(1S,3R)-Methyl 3-Hydroxycyclohexanecarboxylate; (-)-Methyl (1S,3R)-3-Hydroxycyclohexanecarboxylate; Chiral Cyclohexane Derivative; 3-Hydroxycyclohexanecarboxylic Acid Methyl Ester (trans, enantiomerically pure)
EINECS	Contact for details

Quality Control

Our Cyclohexanecarboxylic Acid, 3-Hydroxy-, Methyl Ester, (1S,3R)- is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes rigorous analytical testing, including chiral HPLC, to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.