Description

4-(Methylsulfonyl)Butanoic Acid is a versatile sulfone-containing carboxylic acid building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a reactive carboxylic acid group and a metabolically stable methylsulfonyl moiety, makes it a valuable intermediate for constructing complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting metabolic and inflammatory pathways where the sulfone group can modulate potency and pharmacokinetics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators, where the acid functionality allows for further derivatization.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Material Science Research: Employed in the synthesis of functional monomers and polymers, contributing to materials with specific surface or electronic properties.
• Chemical Biology Probes: Useful for synthesizing activity-based probes and molecular tags to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Item	Detail
Product Name	4-(Methylsulfonyl)Butanoic Acid
CAS No.	148928-08-9
Molecular Formula	C5H10O4S
Molecular Weight	166.20 g/mol
Synonyms	4-(Methanesulfonyl)butanoic acid; 4-Methylsulfonylbutyric acid; γ-(Methylsulfonyl)butyric acid; Butanoic acid, 4-(methylsulfonyl)-; 4-Mesylbutyric acid; 4-(Methylsulfonyl)butyric acid; 148928-08-9 (CAS); 4-(Methylsulphonyl)butanoic acid
EINECS	Contact for details

Quality Control

Our production of 4-(Methylsulfonyl)Butanoic Acid adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, and NMR for comprehensive characterization. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, identity, and impurity profiles. Our quality system is designed to support cGMP and ISO standards for customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed and under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation. Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.