Description

1-(2-Bromo-6-Methyl-Phenyl)-Ethanone is a specialized brominated aromatic ketone building block of significant interest in advanced organic synthesis. Its core value lies in its unique substitution pattern, which provides a reactive handle for further functionalization while the methyl group offers steric and electronic modulation. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a bromo-methyl acetophenone core structure.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the bromine atom facilitates further cross-coupling reactions.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Building block for the synthesis of organic electronic materials, liquid crystals, and advanced polymers.
• Custom Synthesis and Contract Manufacturing: Employed by CDMOs (Contract Development and Manufacturing Organizations) for client-specific, multi-step synthetic routes.
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including Suzuki, Heck, and other palladium-catalyzed couplings.

Basic Information

Product Name	1-(2-Bromo-6-Methyl-Phenyl)-Ethanone
CAS No.	148517-71-9
Molecular Formula	C9H9BrO
Molecular Weight	213.07 g/mol
Synonyms	2'-Bromo-6'-methylacetophenone; 1-(2-Bromo-6-methylphenyl)ethan-1-one; 2-Bromo-6-methylacetophenone; 2-Acetyl-3-bromotoluene; 3'-Bromo-2'-methylacetophenone; α-Bromo-o-methylacetophenone; 2-Methyl-6-bromoacetophenone
EINECS	Contact for details

Quality Control

Our 1-(2-Bromo-6-Methyl-Phenyl)-Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.