Description

2,6-Dichloropyridine-3-Boronic Acid CAS NO 148493-34-9 is a versatile and high-value boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its primary value lies in enabling the precise construction of complex molecules through efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require a reliable, high-purity intermediate for developing active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system, anti-infectives, and oncology therapeutics.
• Agrochemical Synthesis: Used to construct novel pyridine-based herbicides, fungicides, and insecticides, leveraging its halogen and boronic acid functionalities for structural diversification.
• Material Science Research: Employed in the development of organic electronic materials, including ligands for catalysts, organic light-emitting diodes (OLEDs), and conductive polymers.
• Cross-Coupling Reactions: Primarily utilized in Suzuki-Miyaura coupling to form biaryl and heterobiaryl linkages, which are fundamental scaffolds in medicinal and materials chemistry.
• Chemical Biology & Proteomics: Acts as a handle for bioconjugation and the development of molecular probes and inhibitors for studying biological processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and libraries for high-throughput screening.

Basic Information

Product Name	2,6-Dichloropyridine-3-Boronic Acid
CAS No.	148493-34-9
Molecular Formula	C5H4BCl2NO2
Molecular Weight	191.81 g/mol
Synonyms	(2,6-Dichloropyridin-3-yl)boronic acid; 2,6-Dichloro-3-pyridineboronic acid; 3-Borono-2,6-dichloropyridine; 2,6-Dichloro-3-pyridinylboronic acid; B-(2,6-Dichloro-3-pyridinyl)boronic acid; 148493-34-9; 2,6-Dichloro-3-pyridineboronic acid pinacol ester (common protected form)
EINECS	Contact for details

Quality Control

Our 2,6-Dichloropyridine-3-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.