Description

3-Fluoro-5,6-Dihydroquinoline 5,6-Diol is a high-purity fluorinated dihydroquinoline derivative, serving as a critical advanced intermediate in modern organic synthesis. Its unique structure, featuring both a fluorine substituent and a catechol-like diol moiety, makes it a versatile building block for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of fluorinated drug candidates, potentially targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity, stability, and metabolic profile.
• Ligand & Catalyst Development: The diol functionality allows it to act as a precursor or a direct ligand for metal complexes in asymmetric catalysis and material science.
• Organic Electronic Materials: Serves as a building block for fluorinated organic semiconductors, dyes, and photoactive materials due to its conjugated quinoline core.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological processes and enzyme mechanisms.

Basic Information

Product Name	3-Fluoro-5,6-Dihydroquinoline 5,6-Diol
CAS No.	148324-56-5
Molecular Formula	C9H8FNO2
Molecular Weight	181.16 g/mol
Synonyms	5,6-Dihydroxy-3-fluoro-5,6-dihydroquinoline; 3-Fluoro-5,6-dihydroquinoline-5,6-diol; 3-Fluoro-5,6-dihydroxy-1,2,3,4-tetrahydroquinoline; 148324-56-5; 3-Fluoro-5,6-dihydroxy-5,6-dihydroquinoline
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5,6-Dihydroquinoline 5,6-Diol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF for moisture content, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.