Description

1,2-Cyclopropanedicarboxylicacid,1-Methyl-,(1R-Cis)-(9Ci) is a high-purity, chiral cyclopropane derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate its unique stereochemistry into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly those requiring a rigid, three-membered ring structure.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where the cyclopropane moiety imparts specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals for electronics and material science applications.
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic chemistry and process development.

Basic Information

Product Name	1,2-Cyclopropanedicarboxylicacid,1-Methyl-,(1R-Cis)-(9Ci)
CAS No.	148261-95-4
Molecular Formula	C7H10O4
Molecular Weight	158.15 g/mol
Synonyms	(1R,2S)-1-Methylcyclopropane-1,2-dicarboxylic acid; (1R-cis)-1-Methyl-1,2-cyclopropanedicarboxylic Acid; cis-1-Methylcyclopropane-1,2-dicarboxylic Acid; (1R,2S)-1-Methyl-1,2-cyclopropanedicarboxylic acid; 1-Methyl-1,2-cyclopropanedicarboxylic acid, (1R-cis)-; (1R,2S)-1-Methyl-1,2-dicarboxycyclopropane
EINECS	Contact for details

Quality Control

Our 1,2-Cyclopropanedicarboxylicacid,1-Methyl-,(1R-Cis)-(9Ci) is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including chiral purity verification by HPLC. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.